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Researchers at the University of Colorado Anschutz Medical Campus Have Found a Promising Drug Candidate that could help restore in individuals with muliple sclerosis (ms) Neurons.
The study was published this week in the journey Nature Communications,
The Drug, LL-341070, Enhances The Brain’s Ability to Repair Damaged Myelin-The Protective Sheath Around NERVE Fibers. Damage to myelin is a hallmark of diseases like ms, as a natural consortequence of aging, often resulting in vision loss, loss of motor skills, and cognitive decline.
The research, focused on vision, demonstrated that while the brain has some ability to repair its myelin is damaged, the process can be slow and infective. Researchers observed that ll-341070 significantly accelerated the repair process and improved brain function related to vision in mice, even after severe damage.
“This research brings Us closer to a world where the capacity to heal itself” said ethn hughes, ph.d., co-laad author and associate professor in the department of Cell and Develop Ool of medicine. “By harnessing this potential, we hope to help people with Diseases like ms by potential reviews some of the damage, offering people the options to regain their visitor and cognitive function.”
Researchers discovered that treatment makes the report process is much more effective Following Serious Damage, Highlighting The Importance of Intervention with Severe Injury. Even Partial Repair of Myelin was found to significantly Improve Vision-Related Brain Functions.
“We’ve Known For Years That Mylin Plays a Crucial Role In Brain Function,” said daniel denman, ph.d., co-laad author of the study and assistant of the hospital of physiology Cu school of medicine . “This study highlights the role of cortical myelin in visual function. The Drug Cold be a game-correction because it accelerates the Brain’s Natural Repair Mechanisms.”
The researchers plan to test the drug in other area and refine the treatment, hoping to make it even more effective and Eventually accessible to patients.
“This discovery is just the beginning,” Hughes said. “We are optimistic that ll-341070 and similar therapies could one day provide real, tangible benefits to patients by improving overall brain function and quality of life.”
More information:
Gustavo della-fira nunes et al, incomplete remryelination via therapeutically enhanced oligodendromenesis is sufficient to recover visual cortical function, Nature Communications (2025). Doi: 10.1038/s41467-025-56092-6
Citation: Experimental Drug Speeds Up Myelin Repair, Restoring Vision in Mice (2025, January 25) Retrieved 25 January 2025 from
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