A high dietary intake of lean and oily fish may slow the program of disability in People with Multiple Sclerosis (MS), Suggests a Comporative Population-Based Study, Published OnLished On the in the Journal of neurology neurosurgery & psychiatry,

The anti-inflammatory and neuroprotective properties of the nutrients found in fish may be key, say the resarchers, who add that their findings underscore the potential importancy in promotence

Emerging Evidence Indicates that Diet May have a Role in the Development of Inflammatory Diseases, Including MS, Explain the Researchers.

While Previous Published Research Has Linked Fish Consumption with Lower Levels of Disability Among these with MS, Few Studies Have LOKED At Whieth Sloop or Lessen the Progresion of disability, they point out.

To explore this further, they drew on 2,719 newly diagnosed participants (Average age 38) in the epidemiologist Investigation of Multiple Sclerosis (EIMS) Study, A Swedish Nationwide Population-Based Case-Constation Study, all of who was recruited between April 2005 and June 2015.

On entry to eims, all participants provided information on Environmental Exposures and Lifestyle Habits, Including their Consumption of Lean and Oily Fish and Oily Fish, Whoch Was Categorized Ass: Never Or Seller; One to three times a month; And weekly, and scored from 2 to 6, depending on where they ate lean or oily fish, or bot.

Their disease program, measured using the expanded disability status scale (EDSS), was tracked for up to 15 years through the Swedish MS registry.

Confirmed disability Worsening was defined as an increase in the Edss Score of at Least 1 point 1 point from baseline, sustained between two further check-ups, at least six months apart.

The Highest Fish Consumption at Diagnosis was Associated with a 44% Lower Risk of Confirmed Disability Worsening as Well as a 45% Lower Risk of Progressing to Edss 3 and A 43% Lower Risk of Progressing To Edss 4 compared with that who ate none or very little.

And the More Lean and Oily Fish that was consumed, the lower was the risk of confirmed disability and programting to Edss 3 and 4, Trends Analysis indicated.

In 2021, 1,719 participants complete an online follow-up questionnaire which assessed changes in fish intake over time. Some 412 (24%) Had Altered their Fish Consumption: 288 Had Increased It; 124 had decreased it.

Thos who increased their score from 2-3 to a score of 5–6 with 5-6 with years after Diagnosis (133) Had A 20% Lower Lower Risk of Confirmed Disability Worsening, Compared with Thus Thus who has been compared to littele Or no fish (400).

Only 16 participants increase their fish consumption from a baseline score of 2 to a score of 5-6, but they had a 59% lower risk of confirmed disability Worsening, Compared with the Lowast Level of Consumption (101).

The Findings Held True even when the potential influential factors of physical activity, weight (BMI), Smoking, Alcohol Intake, and Sun Exuposure was accounted for. They also Remained Similar when Further Adjustments were made for Vitamin D Levels.

This is an observational study, and as such, no firm conclusions can be drawn about cause and effect. And further research to validate the findings and investigate the underlying biological mechanisms is required, say the reserchers.

But they sugges, “while omega-3 fatty acids, predominantly Sugged that other factors may also play a significant role.

They explain, “Taurine is the most abundant free amino acid in the brain and, although there are endogenous mechanisms for its production, an exogenous supply is Necessary to Meet Physsary to Meet Needs. “

They add, “taurine has diverse cellular functions, include cytoprotative actions through antioxidative and anti-inflammatory effects, making it a aesaepeutic agent for next disorders. “

And they conclude, “The results underscore the potential role of diet, particularly fish consumption, as a modifiable factor that group Complement Existing Therapeutic Strategies for ms.”