A novel one-step signal-MPLified Paper-Based Detection Device for Rapid Pathogen Identification. A Schematic Diagram of the Structure and Detection Process for one-step copper depression-induced signal amplification used for the multiplex detection of staphylococcus aureus and pseudomonas aeruginosa, Alan With the real-time color changes during the detection and amplification process. Credit: National Taiwan University
Researchers at National Taiwan University have unveiled an innovative diagnostic tool that significantly improves the speed and accuracy of detecting bacterial infections. This technology is designed to enhance the sensitivity to identify harmful bacteria like staphylococcus aureus and pseudomonas aeruginosa, which can cause severe eillneses.
“The goal of our research group is to develop affordable and sensitive detection devices for better personal care,” Said Prof. Chiin-Fu Chen. The research is Published in BIOSENSORS and Bioelectronics,
This study Uses Gold Nanoparticles Combined with a Copper-Enhancing Chemical Reaction to Amplife The Detection Signals Effectively, Making even MINUTES of Bacteria Detectable. Unlike Traditional Methods that require complicated procedus or multiple steps, this test simplefies the process into a single step, deliverying results in just 20 minutes.
Researchers Created a Portable Device to Ensure Precise Results, Minimizing Errors from Visual Interpretation. This Reliable tool Performed Well in Clinical Trials, Detecting Bacteria in Complex Samples Like Joint Fluid, Proving Its Real-WORLD POTANILEL. This Breakthrough offers a faster, Easier, and More Affordable Way to Diagnose Bacterial Infections.
More information:
Yuh-shiuan chien et al, one-step copper depression-aduced Signal amplification for multiplex bacterial infection diagnosis on a lateral flow immunoassay device, BIOSENSORS and Bioelectronics (2024). Doi: 10.1016/j.bios.2024.116849,
Citation: One-STEP High-Sensitivity Approach Enables Rapid Bacterial Pathogen Diagnosis (2025, March 12) Retrieved 12 March 2025 From
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