Perfusion Technique for Donor Livers Garners Worldwide Interest

Perfusion Technique for Donor Livers Garners Worldwide Interest


Otto Van Leeuwen (Left) and Vincent de Meijer with the PerfusionMachine of the UMCG. Credit: UMCG

A perfusion Technique Developed At University Medical Center Groningen (UMCG) to Test the Quality of Donor LED to a Record Number of Liver Transplants Last Year; Not only in Groningen, but through the Netherlands. Meanwhile, there is worldwide interest in this performance technique.

Donor livers can only be stored outside the body for a short time, between 6 and 10 hours. The Organ Must Therefore Get to the recipient as Quickly as Possible. As a result, transplants have alloys been under great time pressure. The umcg has had an organ preservation & resuscitation unit since 2015. Transplantation.

With the new perfusion techniques, organs can not only be better preserved but also teso tested just before transplantation. As a result, more organs can be made suitable for transplantation.

Protocol open accessible to every transplant center

The protocol of this performance Technique for Testing Donor Livers have been Published in Nature protocolsHead of the Umcg Comprehensive Transplantation Center Vincent de Meijer and Surgical Resident Otto Van Leeuwen Wrote It Together With Robert Porte, Former Head of the Transplant Center, WHO WORTATATION Center, WHO WORTATION Center Rotterdam.

De Meijer said, “With this publication, the protocol is now accessible to every center in the world that performs liver transplants. It is safe for the recipients and ensures that we can give more patients a new liver and thus a new life. “

Perfusion Technique for Donor Livers Gets Worldwide Followings

Positioning of the liver during machine perfusion. Credit: Nature protocols (2025). Doi: 10.1038/s41596-024-01130-8

Record number of liver transplants

After Umcg Started Using This Technique in 2015, other centers in the Netherlands (Rotterdam and Leiden) Followed a fee year later.

De meijer said, “That LED to Us Being Able to Do A Record Number of 253 Liver Transplants in the Netherlands by 2024. In Groningen We Did 95, which is also a record. Available Donor Livers. 70% of our transplant And almost all of these transplants take place during the day and have become schedule, also as a result of our perfusion Technique. “

Staff from Transplant Centers from Norway, Germany, Israel, Belgium and Australia have already visited the umcg to take a look in the performance kitchen. De Meijer said, ‘Don’t run too fast,’ We say to all centers, do it step by step. Fluid. That is a prerequisite before proceeding to hot performance. “

Apart from needing the right equipment to perform the perfusion Technique, Well-trained staff are also also essential. Otto van leeuwen was involved in the education program for Organ Perfusionists from The BEGINING.

“Worldwide, we are the only ons to organize the International Organ Perfusionist Training Program in the UMCG Since 2022, a course for which students from all over the World Apply EVRY YEVRY Perfusion procedure requires the presence of one or two perfusionists.

More information:
Otto B. van leeuwen et al, ‘back-to-base’ combined hypothermic and normothermic machine performance of human donor livers, Nature protocols (2025). Doi: 10.1038/s41596-024-01130-8

Provided by University Medisch Centrum Groningen

Citation: Perfusion Technique For Donor Livers Garners Worldwide Interest (2025, February 26) Retrieved 27 February 2025 from

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