Maternal Stress Cold Leave Epigenetic Imprints On Genese in the Placenta Associated With Cortisol -A Necessary Hormone for Fetal Development – Randed Affect the Baby ‘ Cording to a paper Published in the journey European neuropsychopharmacology,

The study sugges that a mother’s emotional well-eating during pregnancy is not only important for her, but would also also influence the future health of her baby.

The Study is LED by Lourdes Fañanás, Professor at the Faculty of Biology and the Institute of Biomedicine (Ibub) of the University of Barcelona. She is group leader of the networking biomedical research center on mental health (cibersam) area.

The Study is also LED by Elisabeth Binder, from the Max Plancies Institute of Psychiatry in Munich (Germany). The collaboration of the collabority of the rare diseases of the rare disease, and the experts elise Eixa Eixarch and Fátima Crispi, Who are Also Researches at Ciaberer and AT the Elise Edicine and Health Sciences, Bcnatal (Irsjd and Hospital Clínic – Idibaps).

The Placenta is an essential organ during pregnancy, as it not only provides oxygen and nutrients to the fetus, but also responses to factories such as Maternal Stress and Helps the fetus adapt to its. However, the means by which the placenta adjusts to these stressors and how it influences fetal development remunerals remain revival Unexplred.

The research team observed that maternal stress may leave epigenetic marks on certain placental genes. Specifically, these marks do not modify the genetic structure, but they do alter its function. The study identified epigenetic changes in genes related to the regulation of cortisol, an essential hormone in the body’s response to stress.

Supporting women from the very first stages of pregnancy

The pilot study involved 45 healthy, first-time pregnant women. During pregnancy, their cortisol levels and depressive symptoms was measured and, after delivery, placentas was analyzed. At Seven Weeks, The Neurodevelopment of the Babies was assessed using a specialized test (brazelton’s nbas).

The research team used an advanced sequencing technique that allows them to look at epigenetic changes in large area and thus gain a very detailed View of the Placental Response to Maternal Stresses. This method identified changes in key genes involved in cortisol regulation, such as HSD11B2, NR3C1 and FKBP5.

The results sugges that Maternal Stress – Spectally In Early Pregnancy – CAN CAUSE AALTAREATIONS in these genes, which must be deal fetal development and the future heart of the baby.

Águeda castro, first author of the study and cibersam researcher at the university of barcelona, ​​points ut that “this study reinforces the importance of taking care of the mental hairs Cy, Since Stress Cold Leave a Biological Imprint on the Baby’s Development Through Epigenetic Mechanisms That We Are Just Beginning to Undrstand. “

Ibub selected this article as the best scientific publication of November 2024 for its innovative approach to prenatal and mental health. Although this is a pilot study, the results open the door to future research and possible interventions to support pregnant women in vulnerable situations from the earliest stages.

While These Findings Need to Be Replicated In Larger Studies, This Breakthrough Underscores The Importance of Psychological Care and Emotional Support DURNANCY, not on o for the long-term health of the baby.